I think my overall amusement in relation to Avenue Q must be reflective of the fact that my childhood (aka, from birth to about the age of ten) was pretty much all kids shows featuring muppets and the like. I wasn't really aware of popular culture. I was a Sesame Street, Mister Rogers, Lamb Chop, Fraggle Rock, The Muppet Show, and Shining Time Station kinda gal.
... I must see this show.